Source：GMP GENIUSNuclease is a tag free recombinant form of Serratia marcescens extracellular endonuclease produced in Escherichia coli cells using a proprietary process at ACRObiosystems. GMP GENIUSNuclease DMF Filed is a homodimer with monomer molecular masses about 30 kDa. The enzyme is a non-specific nuclease with high specific activity, which degrades both single- and double-stranded nucleic acids in any form (single stranded, double stranded, linear, circular and supercoiled). It hydrolyzes internal phosphodiester bonds present between the nucleotides to 5’- phosphorylated oligonucleotides of 3-5 bases in length.
Species Reactivity：Serratia marcescens
Host：E. coli
Tag：Native
Exp Region：Asp 22 - Asn 266
Format：Liquid
Conjugate：Unconjugated
Endotoxin：0.01 EU per μg
Purity：95%
Buffer：Supplied as 0.2 μm filtered solution in 20mM Tris, 20mM NaCl, 2mM MgCl2, pH 8.0 with 50% Glycerol as protectant.
