83-3866-55　SARS-CoV-2 （COVID-19） Nucleocapsid protein, His Tag 1mg　NUN-C5221-1mg

特徴

• 背景
• Nucleocapsid (N) protein is the most abundant protein found in coronavirus.
• CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways.
• It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M.
• E., et al.
• 2017, Virology; 517: 62-68).
• The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics.
• Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
• 特徴
• This protein carries a polyhistidine tag at the C-terminus.
• The protein has a calculated MW of 47.3 kDa.
• The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.