TGF type I receptor also called the activin receptor-like kinase 5 (ALK5) and involved in TGF signaling.
TGFβ signaling is mediated by the interaction of TGFβ ligands (TGFβ 1, 2 or 3) with cell surface receptors, the TGF type I, type II and type III receptors.
Signaling is initiated by binding of TGF to the TGF type II receptor forming a ligand-receptor complex which interacts with the TGF type I receptor.
特徴
This protein carries a llama IgG2b Fc tag at the C-terminus.
The protein has a calculated MW of 38.0 kDa.
The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human TGF-beta RI Protein, Llama IgG2b Fc Tag (TG1-H5259) is expressed from human 293 cells (HEK293). It contains AA Leu 34 - Leu 126 (Accession # P36897-1).
Species Reactivity：Human
Host：HEK293
Tag：C-LlamaFc(LlamaIgG2b)
Exp Region：Leu 34 - Leu 126
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P36897-1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：51 mM Tris,100 mM Glycine,25 mM Arginine,150 mM NaCl,pH7.5
