Dengue is a mosquito-borne viral disease widely spread all over the world transmitted by 4 serotypes of dengue virus (DENV).
The symptoms range from mild dengue fever to dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) with high mortality.
Currently, most of the studies on DENV vaccines emphasize on its envelope protein (i.e., Sanofi’s tetravalent dengue vaccine Dengvaxia).
However, the fact pointing out that the vaccines with Envelope protein may could have negative effect on people never infected by DENV which makes the non-structural protein NS1 become another great target for vaccine research with its ability to avoid Antibody Dependent Enhancement.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 41.8 kDa.
The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：DENV2 (strain Thailand/16681/1984) NS1 protein, His Tag (NS1-D52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 776 - Ala 1127 (Accession # P29990-1).
