T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins.
CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex.
T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
特徴
Mouse CD3 epsilon&CD3 gamma Heterodimer Protein, His Tag&Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 15.1 kDa (CD3E) and 15.2 kDa (CD3D).
Subunit CD3E is fused with a polyhistidine tag at the C-terminus and subunit CD3G is fused with a flag tag at the C-terminus.
As a result of glycosylation, the protein migrates as 19-22 kDa under reducing (R) condition, and 35 kDa under non-reducing (NR) condition (SDS-PAGE).
仕様
容量：100ug
Source：Mouse CD3 epsilon&CD3 gamma Heterodimer Protein, His Tag&Flag Tag (CDG-M52D2) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 108 (CD3E) & Gln 23 - Ser 116 (CD3G) (Accession # Q22646-1 (CD3E) & Q11942-1 (CD3G)).
Species Reactivity：Mouse
Host：HEK293
Tag：C-10×His | C-Flag
Exp Region：Asp 23 - Asp 108 (CD3E) & Gln 23 - Ser 116 (CD3G)
