T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins.
CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex.
T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
特徴
The subunit CD3E carries a human IgG1 Fc fragment at the C-terminus, followed by a polyhistidine tag.
The subunit CD3D carries a human IgG1 Fc fragment at the C-terminus, followed by a flag tag.
The protein has a calculated MW of 39.2 kDa (CD3E) and 37.5 kDa (CD3D) .
The protein migrates as 45-55 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
仕様
容量：25ug
Source：MABSol Biotinylated Human CD3E&CD3D Heterodimer Protein, Fc,His Tag&Fc,Flag Tag, primary amine labeling (CDD-H82W0) is expressed from human HEK293 cells. It contains AA Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # NP_000724.1 (CD3E) & NP_000723.1 (CD3D)). It is the biotinylated form of Human CD3E&CD3D Heterodimer Protein, Fc,His Tag&Fc,Flag Tag (CDD-H52W0).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc & C-6×His | C-Fc & C-Flag
Exp Region：Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D)
Format：Powder
Conjugate：Biotin-labeled
Swiss-Prot：P07766-1 (CD3E) & P04234-1 (CD3D)
Protein ID：NP_000724.1 (CD3E) & NP_000723.1 (CD3D)
