T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins.
CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex.
T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
特徴
Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free is produced by co-expression of CD3E and CD3D, has a calculated MW of 16.6 kDa (CD3E) and 13.4 kDa (CD3D).
Subunit CD3E is fused with a polyhistidine tag at the C-terminus and subunit CD3D contains no tag.
The reducing (R) heterodimer protein migrates as 25-30 kDa (CD3E) and 20 kDa and 22 kDa (CD3D) due to glycosylation.
仕様
容量：50ug
Source：Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (CDD-H52W1) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # P07766-1 (CD3E) & P04234-1 (CD3D)).
Species Reactivity：Human
Host：HEK293
Tag：C-8×His | Native
Exp Region：Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D)
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P07766-1 (CD3E) & P04234-1 (CD3D)
Protein ID：NP_000724.1 (CD3E) & NP_000723.1 (CD3D)
