T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins.
CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex.
T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
特徴
Cynomolgus CD3E & CD3D Heterodimer Protein, Llama IgG2b Fc Tag & Llama IgG2b Fc Tag, low endotoxin is produced by co-expression of CD3E and CD3D, has a calculated MW of 41.9 kDa (CD3E) and 40.8 kDa (CD3D).
Subunit CD3E is fused with a llama IgG2b Fc tag at the C-terminus and subunit CD3D is fused with a llama IgG2b Fc tag at the C-terminus.
The predicted N-terminus is Gln 22 (CD3E) & Phe 22 (CD3D).
The reducing (R) protein migrates as 50 kDa and 55-65 kDa due to glycosylation.
仕様
容量：100ug
Source：Cynomolgus CD3E&CD3D Heterodimer Protein, Llama Fc&Llama Fc, low endotoxin (CDD-C5259) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Asp 117 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # Q95LI5-1 (CD3E) & Q95LI8-1 (CD3D)).
Species Reactivity：Cynomolgus
Host：HEK293
Tag：C-LlamaFc(LlamaIgG2b) | C-LlamaFc(LlamaIgG2b)
Exp Region：Gln 22 - Asp 117 (CD3E) & Phe 22 - Ala 105 (CD3D)
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q95LI5-1 (CD3E) & Q95LI8-1 (CD3D)
Protein ID：NP_001270544.1 (CD3E) & NP_001274617.1 (CD3D)
Endotoxin：0.01 EU per μg
Purity：90%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
