ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes.
The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2).
ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.
特徴
This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 33.4 kDa.
The protein migrates as 40-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human ASGR1 Protein, His,Avitag (GS1-H82Q3) is expressed from human 293 cells (HEK293). It contains AA Gln 62 - Leu 291 (Accession # P07306-1).
