Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family.
IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain.
IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8.
IL1RL1 possibly involved in helper T-cell function.
IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 61.5 kDa.
The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Mouse IL-1RL1, Fc Tag (IL1-M5259) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Arg 332 (Accession # P14719-1).
Species Reactivity：Mouse
Host：HEK293
Tag：C-Fc
Exp Region：Ser 27 - Arg 332
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P14719-1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
