Interleukin 39 (IL-39) is a new member of the IL-12 family and is composed of IL-23p19 and Ebi3 subunits.The two subunits, IL-23p19 and Ebi3, are shared with IL-23 and IL-27/IL-35.
IL-23p19 is a four-helix bun dle and has homology with IL-6 and granulocyte colony stimulating factor.
Ebi3 was first identified in B lympho cytes infected with EB virus.
Some studies have reported that The combination of IL-23R and gp130 forms the IL-39 receptor.
At present, a research on IL-39 is still in its initial stage, and many issues have not been solved.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 69.4 kDa.
The protein migrates as 75-85 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human IL-39, Fc Tag (IL9-H5259) is expressed from human 293 cells (HEK293). It contains AA Arg 21 - Lys 229 & Arg 20 - Pro 189 (Accession # Q14213-1 (IL-27 beta) & Q9NPF7-1 (IL-23 alpha)).
