Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family.
Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules.
Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages.
The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.
特徴
This protein carries a polyhistidine tag at the C-terminus.
This protein contains an Activation peptide(17 Q-114 I), and will be partially processed into Pro form with calculated MW of 39 kDa and mature form with calculated MW of 28 kDa under reducing (R) condition.
仕様
容量:50ug
Source:Human Cathepsin S, His Tag (CTS-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 17 - Ile 331 (Accession # P25774-1).