CD43 or leukosialin or sialophorin, is predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration.
In hematopathology, CD43 is often considered as a T-cell associated marker, because it is expressed by over 95% of thymocytes and peripheral blood T cells.
CD43 positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN).
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 25.3 kDa.
The protein migrates as 45-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human CD43, His Tag (CD3-H52H9) is expressed from human 293 cells (HEK293). It contains AA Ser 20 - Arg 253 (Accession # P16150-1 ).
