MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily.
MICA contains one Ig-like C1-type (immunoglobulin-like) domain.
Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin.
MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells.
MICA is ligand for the KLRK1/NKG2D receptor.
MICA bind to KLRK1 leads to cell lysis.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 36.4 kDa.
The protein migrates as 52-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human MICA, His,Avitag (MIA-H82E6) is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Gln 308 (Accession # Q29983-1).
