EDIL3，also known as Del1, is a novel extracellular matrix protein encoding three Notch-like epidermal growth factor repeats, an RGD motif, and two discoidin domains.
EDIL3 is expressed in an endothelial cell-restricted pattern during early development.
EDIL3 might involves autocrine angiogenic pathway for the embryonic endothelium, and this function is mediated in part by productive ligation of integrin alpha V beta 3.
Overall, EDIL3 plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development.
Moreover, It also influences endothelial cell behavior.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 77.8 kDa.
The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human EDIL3, Fc Tag (ED3-H5259) is expressed from human 293 cells (HEK293). It contains AA Asp 24 - Glu 480 (Accession # O43854-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Asp 24 - Glu 480
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：O43854-1
Protein ID：NP_005702.3
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
