Interleukin (IL)-21, IL-2, IL-4, IL-7, IL-9, and IL-15 form a family of cytokines based on their sharing the common cytokine receptor γ chain (γc), which was originally discovered as the third receptor component of the IL-2 receptor,IL-2RG.
IL-21 is a class I cytokine that exerts pleiotropic effects on both innate and adaptive immune responses.
It signals through a heterodimeric receptor complex consisting of the IL-21 receptor (IL-21R) and the common γ-chain.
特徴
This protein .
The protein has a calculated MW of 51.5 kDa (IL-21 R) & 53.6 kDa (IL-2 R gamma).
The protein migrates as 65 kDa and 70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:100ug
Source:Human IL-21 R & IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag (ILA-H52W9) is expressed from human 293 cells (HEK293). It contains AA Cys 20 - Pro 236 (IL-21 R) & Leu 23 - Asn 254 (IL-2 R gamma) (Accession # Q9HBE5-1 (IL-21 R) & P31785-1 (IL-2 R gamma)).
Species Reactivity:Human
Host:HEK293
Tag:C-Fc | C-Fc
Exp Region:Cys 20 - Pro 236 (IL-21 R) & Leu 23 - Asn 254 (IL-2 R gamma)
Format:Powder
Conjugate:Unconjugated
Swiss-Prot:Q9HBE5-1 (IL-21 R) & P31785-1 (IL-2 R gamma)