83-3861-77 Human IGFBP-3 R / TMEM219 Protein, Fc Tag （MALS verified） 100ug IGR-H5259-100ug
特徴
- 背景
- IGFBP-3 R, also know as TMEM219, is a cell death receptor specific for IGFBP3.
- IGFBP-3R is expressed on the cell surface, interacts specifically with IGFBP-3 but not other IGFBP species.
- It activates initiator caspase-8, and mediates IGFBP-3-induced apoptosis in vitro and tumor suppression in vivo.
- 特徴
- This protein carries a human IgG1 Fc tag at the C-terminus.
- The protein has a calculated MW of 44.3 kDa.
- The protein migrates as 58-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：100ug
- Source：Human IGFBP-3 R, Fc Tag (IGR-H5259) is expressed from human 293 cells (HEK293). It contains AA Ser 39 - Arg 204 (Accession # Q86XT9-1).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-Fc
- Exp Region：Ser 39 - Arg 204
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：Q86XT9-1
- Endotoxin：1.0 EU per μg
- Purity：90%
- Buffer：PBS, pH7.4
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