Human leukocyte antigen-G (HLA-G) is a group of closely linked genes located on the short arm of human chromosome 6.
Hla-g belongs to a non-classical major histocompatibility complex.
MHC class I molecules are selectively highly expressed in extravvillous trophoblast cells invading the uterine decidual membrane.The gene structure of HLA-G is similar to that of HLA-A,HLA-B and HLA-C, but the termination code appears in advance so that the intracellular segment of protein product encoded by HLA-G is only 6 amino acids, which is significantly shorter than the 30 amino acids of classical HLA classI antigen.
The Human HLA-G & B2M & RIIPRHLQL Complex Protein is a complex of HLA-G of the MHC Class I, B2M and RMFPNAPYL peptide.
特徴
Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein is assembled by biotinylated monomer (HLM-H82E4) and streptavidin.Biotinylated Human HLA-G&B2M&Peptide (RIIPRHLQL) Complex Protein is produced by co-expression of HLA and B2M loaded with RIIPRHLQL peptide.
Biotinylated Human HLA-G&B2M&Peptide (RIIPRHLQL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 36.3 kDa, 13.9 kDa and 13.3 kDa.
The protein migrates as 42-45 kDa and 15 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-H52E9) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-G) & Ile 21 - Met 119 (B2M) & RIIPRHLQL peptide (Accession # P17693-1 (HLA-G) & P61769 (B2M) & RIIPRHLQL).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His
Exp Region：Gly 25 - Ile 308 (HLA-G) & Ile 21 - Met 119 (B2M) & RIIPRHLQL peptide
