Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7).
KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 51.0 kDa.
The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:100ug
Source:Human KIR2DL3, Fc Tag (KI3-H5258) is expressed from human 293 cells (HEK293). It contains AA His 22 - His 245 (Accession # P43628-1).
Species Reactivity:Human
Host:HEK293
Tag:C-Fc
Exp Region:His 22 - His 245
Format:Powder
Conjugate:Unconjugated
Swiss-Prot:P43628-1
Endotoxin:1.0 EU per μg
Purity:95%
Buffer:51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5