CCL14 has weak activity on human monocytes and acts via receptors that also recognize MIP-1 alpha.
It induces intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes.
Enhances the proliferation of CD34 myeloid progenitor cells.
The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes, eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 10.7 kDa.
The protein migrates as 14-15 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human CCL14, His Tag (CC4-H5249) is expressed from human 293 cells (HEK293). It contains AA Thr 20 - Asn 93 (Accession # Q16627-1).
