CCL7, also known as monocyte chemotactic protein-3 (MCP-3), is a CC (cysteine–cysteine) chemokine that is 11–18 kDa in size depending on the level of glycosylation.
Its gene has been mapped to chromosome 17q11.2-q12 and is expressed in response to endogenous cytokines or exogenous bacterial products.
This protein shares 60–71% homology with MCP-1 and MCP-2 chemokines and consequently binds similar receptors.
Receptors CCR1, CCR2, CCR3, and CCR5 have been identified to bind CCL7 in both progenitor and immune cells.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 10.8 kDa.
The protein migrates as 14 kDa and 18-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human CCL7, His Tag (CC7-H52H6) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Leu 99 (Accession # P80098-1).
