83-3859-52 Human IFN-alpha 1 Protein, Fc Tag （MALS verified） 1mg IFA-H5258-1mg
特徴
- 背景
- Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family.
- Interferons alpha-1 and alpha-13 have identical protein sequences.
- Produced by macrophages, IFN-alpha have antiviral activities.
- Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
- IFN-alpha can either suppress or promote the development of autoimmune diabetes.
- It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes.
- 特徴
- This protein carries a human IgG1 Fc tag at the C-terminus.
- The protein has a calculated MW of 45.8 kDa.
- The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：1mg
- Source：Human IFN-alpha 1, Fc Tag (IFA-H5258) is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 189 (Accession # P01562-1).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-Fc
- Exp Region：Cys 24 - Glu 189
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：P01562-1
- Protein ID：NP_076918.1
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：51 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
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