83-3859-43　Human CLEC4C / BDCA2 Protein, His Tag 100ug　CLC-H5245-100ug

特徴

• 背景
• CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303.
• Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell.
• Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man.
• Binds to serum IgG.
• Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells.
• May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells.
• May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
• 特徴
• This protein carries a polyhistidine tag at the N-terminus.
• The protein has a calculated MW of 26.6 kDa.
• The protein migrates as 33-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.