Anterior gradient 2 (AGR2) is a normal endoplasmic reticulum protein that has two important abnormal functions, amphibian limb regeneration and human cancer metastasis promotion.
These normal intracellular and abnormal extracellular roles can be attributed to the multidomain structure of AGR2.
The NMR structure shows that AGR2 consists of an unstructured N-terminal region followed by a thioredoxin fold.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 19.8 kDa.
The protein migrates as 23 kDa and 24 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Mouse AGR2, His Tag (AG2-M52H6) is expressed from human 293 cells (HEK293). It contains AA Lys 21 - Leu 175 (Accession # O88312-1).
