Nucleolin is the major nucleolar protein of growing eukaryotic cells.
It is found associated with intranucleolar chromatin and pre-ribosomal particles.
It induces chromatin decondensation by binding to histone H1.
It is thought to play a role in pre-rRNA transcription and ribosome assembly.
May play a role in the process of transcriptional elongation.
Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
特徴
This protein carries a mouse IgG2a Fc tag at the C-terminus.
The protein has a calculated MW of 103.5 kDa.
The protein migrates as 130-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human Nucleolin, Mouse IgG2a Fc Tag (NUL-H5254) is expressed from human 293 cells (HEK293). It contains AA Val 2 - Glu 710 (Accession # P19338-1).
