Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones.
During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain.
FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair.
The dysregulation of FGF–FGFR was observed in different types of diseases, disorders, and cancers.
Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 23.4 kDa.
The protein migrates as 28 kDa under reducing (R) condition (SDS-PAGE).
仕様
容量：1mg
Source：Human FGF19, His Tag (FG9-H51H3) is expressed from E. coli cells. It contains AA Leu 25 - Lys 216 (Accession # O95750-1).
