Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers.
GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail.
The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains.
GPA33 may play a role in cell-cell recognition and signaling.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 50.1 kDa.
The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human GPA33, Fc Tag (GP3-H5253) is expressed from human 293 cells (HEK293). It contains AA Ile 22 - Val 235 (Accession # Q99795-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Ile 22 - Val 235
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q99795-1
Protein ID：NP_005805.1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
