83-3856-43　Human ZNRF3 protein, His Tag （MALS verified） 100ug　ZN3-H52H3-100ug

特徴

• 背景
• The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling.
• ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.
• 特徴
• This protein carries a polyhistidine tag at the C-terminus.
• The protein has a calculated MW of 19.7 kDa.
• The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

仕様

• 容量：100ug
• Source：Human ZNRF3, His Tag (ZN3-H52H3) is expressed from human 293 cells (HEK293). It contains AA Lys 56 - Met 219 (Accession # Q9ULT6-1).
• Species Reactivity：Human
• Host：HEK293
• Tag：C-10×His
• Exp Region：Lys 56 - Met 219
• Format：Powder
• Conjugate：Unconjugated
• Swiss-Prot：Q9ULT6-1
• Protein ID：NP_001193927.1
• Endotoxin：1.0 EU per μg
• Purity：95%
• Buffer：PBS, pH7.4
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