CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily.
CD27 / TNFRSF7 is found in most T-lymphocytes.
CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity.
It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK.
CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
特徴
This protein carries a mouse IgG2a Fc tag at the C-terminus.
The protein has a calculated MW of 45.1 kDa.
The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Mouse CD27 Protein, Mouse IgG2a Fc Tag (CD7-M5252) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Arg 182 (Accession # P41272-1).
Species Reactivity：Mouse
Host：HEK293
Tag：C-mFc(mIgG2a)
Exp Region：Thr 21 - Arg 182
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P41272-1
Protein ID：NP_001028298.1
Endotoxin：0.1 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
