83-3855-83 Human Transthyretin / Prealbumin Protein, His Tag 1mg TTR-H5223-1mg
特徴
- 背景
- Transthyretin (TTR) is also known as Prealbumin, ATTR, TBPA, PALB, which belongs to the transthyretin family.
- Transthyretin / TTR is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol.
- In cerebrospinal fluid TTR is the primary carrier of T4.
- TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF.
- Less than 1% of TTR's T4 binding sites are occupied in blood.
- TTR misfolding and aggregation is known to be associated with the amyloid diseases.
- 特徴
- This protein carries a polyhistidine tag at the C-terminus.
- The protein has a calculated MW of 14.9 kDa.
- The protein migrates as 17 kDa and 33 kDa under reducing (R) condition (SDS-PAGE) due to the monomer and dimer respectively.
仕様
- 容量：1mg
- Source：Human Transthyretin, His Tag (TTR-H5223) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Glu 147 (Accession # NP_000362).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-8×His
- Exp Region：Gly 21 - Glu 147
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：P02766
- Protein ID：NP_000362
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：PBS, pH7.4
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