83-3854-97 Cynomolgus CLEC4C / BDCA2 Protein, His Tag （MALS verified） 100ug CLC-C52H4-100ug
特徴
- 背景
- CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303.
- Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell.
- Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man.
- Binds to serum IgG.
- Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells.
- May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells.
- May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
- 特徴
- This protein carries a polyhistidine tag at the N-terminus.
- The protein has a calculated MW of 26.1 kDa.
- The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：100ug
- Source：Cynomolgus CLEC4C, His Tag (CLC-C52H4) is expressed from human 293 cells (HEK293). It contains AA Tyr 48 - Ile 212 (Accession # A0A2K5UWP4-1).
- Species Reactivity：Cynomolgus
- Host：HEK293
- Tag：N-10×His
- Exp Region：Tyr 48 - Ile 212
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：A0A2K5UWP4-1
- Protein ID：XP_005570080.1
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：PBS, pH7.4
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