Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201.
PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists.
PROCR is probably released by a metalloprotease.
PROCR seems to have the same activity as the membrane-bound form.
PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung.
PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex.
PROCR plays a role in the protein C pathway controlling blood coagulation.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 48.6 kDa.
The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human PROCR, Fc Tag (PRR-H5254) is expressed from human 293 cells (HEK293). It contains AA Ser 18 - Thr 209 (Accession # AAH14451).
