83-3852-07　Human Mucin-1 / MUC-1 （116-173） Protein, Fc Tag 1mg　MU1-H5153-1mg

特徴

• 背景
• Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction.
• MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites.
• Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization.
• Probably plays a role in maintaining homeostasis on mucosal surfaces.
• 特徴
• This protein carries a human IgG1 Fc tag at the C-terminus.
• The protein has a calculated MW of 32.7 kDa.
• The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE).

仕様

• 容量：1mg
• Source：Human Mucin-1 (116-173), Fc Tag (MU1-H5153) is expressed from E. coli cells. It contains AA Ser 116 - Gly 173 (Accession # P15941-8).
• Species Reactivity：Human
• Host：E. coli
• Tag：C-Fc
• Exp Region：Ser 116 - Gly 173
• Format：Powder
• Conjugate：Unconjugated
• Swiss-Prot：P15941-8
• Endotoxin：1.0 EU per μg
• Purity：95%
• Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
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