The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types.
Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection.
It is one of the three experimentally described colony-stimulating factors.
M-CSF binds to the colony stimulating factor 1 receptor.
Macrophage colony-stimulating factor has been shown to interact with PIK3R2.
M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells.
Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 26.0 kDa.
The protein migrates as 36-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：Human M-CSF, His Tag (MCF-H5247) is expressed from human 293 cells (HEK293). It contains AA Glu 33 - Arg 255 (Accession # P09603-1).
