Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis.
The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4.
The encoded protein may be involved in the moderation of asthma and allergic diseases.
The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals.
Three transcript variants encoding the same protein have been found for this gene.
HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair.
In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 31.5 kDa.
The protein migrates as 60-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human TIM-1 / HAVCR1, His Tag (KI1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Gly 295 (Accession # Q96D42-1).
