83-3850-69 Human PTK7 / CCK4 Protein, Fc Tag （MALS verified） 1mg PT7-H5253-1mg
特徴
- 背景
- PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes.
- Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle.
- Also expressed in erythroleukemia cells.
- Inactive tyrosine kinase involved in Wnt signaling pathway.
- Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway.
- Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis.
- Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
- 特徴
- This protein carries a human IgG1 Fc tag at the C-terminus.
- The protein has a calculated MW of 101.1 kDa.
- The protein migrates as 125-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：1mg
- Source：Human PTK7, Fc Tag (PT7-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 31 - Thr 704 (Accession # Q13308-1).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-Fc
- Exp Region：Ala 31 - Thr 704
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：Q13308-1
- Protein ID：NP_002812.2
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
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