Integrin alpha 11 beta 1 is a receptor for collagen.
The alpha11 cDNA encodes a mature protein with a large 1120-residue extracellular domain that contains an I-domain of 207 residues and is linked by a transmembrane domain to a short cytoplasmic domain of 24 amino acids.
The deduced alpha11 protein shows the typical structural features of integrin alpha-subunits and is similar to a distinct group of alpha-subunits from collagen-binding integrins.
特徴
Mouse ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA11 and ITGB1, has a calculated MW of 132.0 kDa (ITGA11) and 83.5 kDa (ITGB1).
Subunit ITGA11 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus.
The reducing (R) protein migrates as 105-116 kDa and 150 kDa due to glycosylation.
仕様
容量：1mg
Source：Mouse ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-M52W5) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Pro 1141 (ITGA11) & Gln 21 - Asp 728 (ITGB1) (Accession # P61622-1 (ITGA11) & P09055-1 (ITGB1)).
Species Reactivity：Mouse
Host：HEK293
Tag：C-10×His | Native
Exp Region：Phe 23 - Pro 1141 (ITGA11) & Gln 21 - Asp 728 (ITGB1)
