Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1.
The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1.
The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development.
In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.
特徴
Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His,Avitag&Tag Free, produced by co-expression of ITGA8 and ITGB1, has a calculated MW of 116.4 kDa (ITGA8) and 83.7 kDa (ITGB1).
Subunit ITGA8 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and an Avi tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus.
The non-reducing (NR) protein migrates as 140-150 kDa (ITGA8) and 100-115 kDa (ITGB1) respectively due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (IT1-H82Wb) is expressed from human 293 cells (HEK293). It contains AA Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1) (Accession # P53708-1 (ITGA8) & P05556-1 (ITGB1)).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His & C-Avi | Native
Exp Region：Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1)
