Integrin alpha 11 beta 1 is a receptor for collagen.
The alpha11 cDNA encodes a mature protein with a large 1120-residue extracellular domain that contains an I-domain of 207 residues and is linked by a transmembrane domain to a short cytoplasmic domain of 24 amino acids.
The deduced alpha11 protein shows the typical structural features of integrin alpha-subunits and is similar to a distinct group of alpha-subunits from collagen-binding integrins.
特徴
Human ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA11 and ITGB1, has a calculated MW of 131.6 kDa (ITGA11) and 82.7 kDa (ITGB1).
Subunit ITGA11 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus.
The reducing (R) protein migrates as 150-165 kDa (ITGA11) and 90-120 kDa (ITGB1) respectively due to glycosylation.
仕様
容量：1mg
Source：Human ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Pro 1141 (ITGA11) & Gln 21-Asp 728 (ITGB1) (Accession # Q9UKX5-1 (L524R) (ITGA11) & P05556-1 (ITGB1)).
