CD24 may have a pivotal role in cell differentiation of different cell types.
Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor.
Modulates B-cell activation responses.
Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.
Plays a role in the control of autoimmunity.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 29.3 kDa.
The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Biotinylated Cynomolgus CD24, Fc Tag, primary amine labeling (CD4-C8254) is expressed from human 293 cells (HEK293). It contains AA Thr 27 - Lys 54 (Accession # I7GKK1-1).
