Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family.
IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain.
IL1RAP is detected in liver, skin, placenta, thymus and lung.
IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 40.2 kDa.
The protein migrates as 50-61 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human IL-1 RAcP, His Tag (ILP-H5225) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3).
