83-3849-13 Human PTK7 / CCK4 Protein, His Tag （MALS verified） 1mg PT7-H52H3-1mg
特徴
- 背景
- PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes.
- Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle.
- Also expressed in erythroleukemia cells.
- Inactive tyrosine kinase involved in Wnt signaling pathway.
- Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway.
- Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis.
- Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
- 特徴
- This protein carries a polyhistidine tag at the C-terminus.
- The protein has a calculated MW of 76.5 kDa.
- The protein migrates as 90-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：1mg
- Source：Human PTK7, His Tag (PT7-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 31 - Thr 704 (Accession # Q13308-1).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-10×His
- Exp Region：Ala 31 - Thr 704
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：Q13308-1
- Protein ID：NP_002812.2
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：PBS, pH7.4
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