Interleukin-17 receptor E (IL-17 RE) is an orphan receptor of the IL-17 receptor family, also known as UNQ3056, PRO9877, IL-17 Receptor E.
IL-17RE is known to be expressed in the pancreas, brain, and prostate.
IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection.
IL-17C functioned in a unique autocrine manner, binding to a receptor complex consisting of the receptors IL-17RA and IL-17RE, which was preferentially expressed on tissue epithelial cells.
Some data identify IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 60.5 kDa.
The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human IL-17 RE (155-454), Fc Tag (ILE-H5256) is expressed from human 293 cells (HEK293). It contains AA Thr 155 - His 454 (Accession # Q8NFR9-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Thr 155 - His 454
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q8NFR9-1
Protein ID：NP_705613.1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
