Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA.
IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity.
Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 75.9 kDa.
The protein migrates as 90-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human IL-17 RC, Fc Tag (ILC-H5259) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - His 465 (Accession # NP_703190.2).
