Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily.
IL27RA contains three fibronectin type-III domains.
IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes.
IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27.
IL27RA involved in the regulation of Th1-type immune responses.
IL27RA also appears to be involved in innate defense mechanisms.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 78.7 kDa.
The protein migrates as 100-116 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human IL-27 Ra, Fc Tag (ILA-H5254) is expressed from human 293 cells (HEK293). It contains AA Gln 33 - Arg 514 (Accession # AAH28003).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Gln 33 - Arg 514
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q6UWB1-1
Protein ID：AAH28003
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
