Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily.
This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3.
The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 34.9 kDa.
The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Canine IL-3 R alpha, His Tag (ILA-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 33 - Asp 315 (Accession # XP_038305195.1).
