The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9).
All family members possess three immunoglobulin (Ig)-like domains in their extracellular region.
Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family.
Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 62.4 kDa.
The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human IL-1 Rrp2, Fc Tag (IL2-H5254) is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Arg 335 (Accession # Q9HB29-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Asp 20 - Arg 335
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q9HB29-1
Protein ID：NP_003845.2
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
