Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds.
Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport).
特徴
This protein carries no "tag".
The protein has a calculated MW of 24.8 kDa.
The protein migrates as 28-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:1mg
Source:Rabbit IgG Fc, Tag Free (IGG-R5203) is expressed from human 293 cells (HEK293). It contains AA Cys 105 - Lys 323 (Accession # P01870-1).
Species Reactivity:Rabbit
Host:HEK293
Tag:Native
Exp Region:Cys 105 - Lys 323
Format:Powder
Conjugate:Unconjugated
Swiss-Prot:P01870-1
Endotoxin:1.0 EU per μg
Purity:95%
Buffer:50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5