83-3846-71 Llama IgG2b Fc Protein, Tag Free （MALS verified） 200ug IGB-L5204-200ug
特徴
- 背景
- Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells.
- In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment.
- The Fc segment bears a highly conserved N-glycosylation site.
- There are two members of IgG2: IgG2a and IgG2b.
- It was found that IgG2a was superior to IgG1 in activating complement.
- The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
- Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).
- 特徴
- This protein carries no "tag".
- The protein has a calculated MW of 27.3 kDa.
- The protein migrates as 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：200ug
- Source：Llama IgG2b Fc, Tag Free (IGB-L5204) is expressed from human 293 cells (HEK293). It contains AA Glu 1-Ser 243 (Accession # AAX73259.1).
- Species Reactivity：Llama
- Host：HEK293
- Tag：Native
- Exp Region：Glu 1-Ser 243
- Format：Powder
- Conjugate：Unconjugated
- Protein ID：AAX73259.1
- Endotoxin：1.0 EU per μg
- Purity：90%
- Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
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