Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells.
In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment.
The Fc segment bears a highly conserved N-glycosylation site.
There are two members of IgG2: IgG2a and IgG2b.
It was found that IgG2a was superior to IgG1 in activating complement.
The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
特徴
This protein carries an Avi tag (Avitag) at the C-terminus.
The protein has a calculated MW of 28.2 kDa.
The protein migrates as 32-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：500ug
Source：Biotinylated Mouse IgG2a Fc, Avitag (IGA-M8210) is expressed from human 293 cells (HEK293). It contains AA Glu 98 - Lys 330 (Accession # P01863).
Species Reactivity：Mouse
Host：HEK293
Tag：C-Avi
Exp Region：Glu 98 - Lys 330
Format：Powder
Conjugate：Biotin-labeled
Swiss-Prot：P01863
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
